09.24.07
Vitamin D for type 2 diabetics
Interesting finding. I take 1400 IU of Vitamin D in supplements daily.
In a study involving 462 consecutive type 2 diabetic patients with mild kidney dysfunction (mean age = 62 years), an independent association was observed between decreased serum 25-hydroxyvitamin D [25(OH)D] concentrations and prevalent cardiovascular disease (CVD). Kidney function was strongly and inversely associated with CVD. Using multivariate logistic regression analysis, an inverse association was observed between serum 25(OH)D concentrations and prevalent CVD (odds ratio = 0.95), independent of baseline kidney function and other known risk factors. Additionally, after adjusting for potential confounders, the inverse association between serum 25(OH)D concentrations and CVD remained statistically significant in patients in the lowest tertile for estimated glomerular filtration rate. Thus, the results of this study suggest that inadequate vitamin D status in type 2 diabetic patients with mild kidney dysfunction may be associated with prevalent CVD.
“Association between 25-hydroxyvitamin D deficiency and cardiovascular disease in type 2 diabetic patients with mild kidney dysfunction,” Chonchol M, Cigolini M, Targher G, Nephrol Dial Transplant, 2007 Sep 17; [Epub ahead of print]. (Address: Michel Chonchol, MD, University of Colorado Health Sciences Center, Division of Renal Diseases and Hypertension; Box C-281, Denver, CO 80262, USA. Email: michel.chonchol@uchsc.edu ).
